PhytophthoraV1, Main, Exploration, bibRecord, 000192

G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.

Identifieur interne : 000192 ( Main/Exploration ); précédent : 000191; suivant : 000193

G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.

Auteurs : Min Qiu [République populaire de Chine] ; Yaning Li [République populaire de Chine] ; Xin Zhang [République populaire de Chine] ; Mingrun Xuan [République populaire de Chine] ; Baiyu Zhang [République populaire de Chine] ; Wenwu Ye [République populaire de Chine] ; Xiaobo Zheng [République populaire de Chine] ; Francine Govers [Pays-Bas] ; Yuanchao Wang [République populaire de Chine]

Source :

PLoS pathogens [ 1553-7374 ] ; 2020.

RBID : pubmed:31961913

Descripteurs français

KwdFr :
- Domaines protéiques (MeSH), Liaison aux protéines (MeSH), Maladies des plantes (parasitologie), Noyau de la cellule (génétique), Noyau de la cellule (métabolisme), Phytophthora (croissance et développement), Phytophthora (enzymologie), Phytophthora (génétique), Phytophthora (pathogénicité), Protein-Serine-Threonine Kinases (composition chimique), Protein-Serine-Threonine Kinases (génétique), Protein-Serine-Threonine Kinases (métabolisme), Soja (parasitologie), Sous-unités alpha des protéines G (composition chimique), Sous-unités alpha des protéines G (génétique), Sous-unités alpha des protéines G (métabolisme), Spores (croissance et développement), Spores (enzymologie), Spores (génétique), Spores (métabolisme), Transport des protéines (MeSH), Virulence (MeSH).
MESH :
- composition chimique : Protein-Serine-Threonine Kinases, Sous-unités alpha des protéines G.
- croissance et développement : Phytophthora, Spores.
- enzymologie : Phytophthora, Spores.
- génétique : Noyau de la cellule, Phytophthora, Protein-Serine-Threonine Kinases, Sous-unités alpha des protéines G, Spores.
- métabolisme : Noyau de la cellule, Protein-Serine-Threonine Kinases, Sous-unités alpha des protéines G, Spores.
- parasitologie : Maladies des plantes, Soja.
- pathogénicité : Phytophthora.
- Domaines protéiques, Liaison aux protéines, Transport des protéines, Virulence.

English descriptors

KwdEn :
- Cell Nucleus (genetics), Cell Nucleus (metabolism), GTP-Binding Protein alpha Subunits (chemistry), GTP-Binding Protein alpha Subunits (genetics), GTP-Binding Protein alpha Subunits (metabolism), Phytophthora (enzymology), Phytophthora (genetics), Phytophthora (growth & development), Phytophthora (pathogenicity), Plant Diseases (parasitology), Protein Binding (MeSH), Protein Domains (MeSH), Protein Transport (MeSH), Protein-Serine-Threonine Kinases (chemistry), Protein-Serine-Threonine Kinases (genetics), Protein-Serine-Threonine Kinases (metabolism), Soybeans (parasitology), Spores (enzymology), Spores (genetics), Spores (growth & development), Spores (metabolism), Virulence (MeSH).
MESH :
- chemical , chemistry : GTP-Binding Protein alpha Subunits, Protein-Serine-Threonine Kinases.
- enzymology : Phytophthora, Spores.
- genetics : Cell Nucleus, GTP-Binding Protein alpha Subunits, Phytophthora, Protein-Serine-Threonine Kinases, Spores.
- growth & development : Phytophthora, Spores.
- metabolism : Cell Nucleus, GTP-Binding Protein alpha Subunits, Protein-Serine-Threonine Kinases, Spores.
- parasitology : Plant Diseases, Soybeans.
- pathogenicity : Phytophthora.
- Protein Binding, Protein Domains, Protein Transport, Virulence.

Abstract

Eukaryotic heterotrimeric guanine nucleotide-binding proteins consist of α, β, and γ subunits, which act as molecular switches to regulate a number of fundamental cellular processes. In the oomycete pathogen Phytophthora sojae, the sole G protein α subunit (Gα; encoded by PsGPA1) has been found to be involved in zoospore mobility and virulence, but how it functions remains unclear. In this study, we show that the Gα subunit PsGPA1 directly interacts with PsYPK1, a serine/threonine protein kinase that consists of an N-terminal region with unknown function and a C-terminal region with a conserved catalytic kinase domain. We generated knockout and knockout-complemented strains of PsYPK1 and found that deletion of PsYPK1 resulted in a pronounced reduction in the production of sporangia and oospores, in mycelial growth on nutrient poor medium, and in virulence. PsYPK1 exhibits a cytoplasmic-nuclear localization pattern that is essential for sporangium formation and virulence of P. sojae. Interestingly, PsGPA1 overexpression was found to prevent nuclear localization of PsYPK1 by exclusively binding to the N-terminal region of PsYPK1, therefore accounting for its negative role in sporangium formation. Our data demonstrate that PsGPA1 negatively regulates sporangium formation by repressing the nuclear localization of its downstream kinase PsYPK1.

DOI: 10.1371/journal.ppat.1008138
PubMed: 31961913
PubMed Central: PMC7010300

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000294
to stream Main, to step Curation: 000294

Le document en format XML

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<author><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name>
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<author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.</title>
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<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
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<author><name sortKey="Li, Yaning" sort="Li, Yaning" uniqKey="Li Y" first="Yaning" last="Li">Yaning Li</name>
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<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
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<author><name sortKey="Zhang, Xin" sort="Zhang, Xin" uniqKey="Zhang X" first="Xin" last="Zhang">Xin Zhang</name>
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<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
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<author><name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
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<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
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<author><name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
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<author><name sortKey="Govers, Francine" sort="Govers, Francine" uniqKey="Govers F" first="Francine" last="Govers">Francine Govers</name>
<affiliation wicri:level="4"><nlm:affiliation>Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands.</nlm:affiliation>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Laboratory of Phytopathology, Wageningen University, Wageningen</wicri:regionArea>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu</wicri:regionArea>
<wicri:noRegion>Jiangsu</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu</wicri:regionArea>
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<series><title level="j">PLoS pathogens</title>
<idno type="eISSN">1553-7374</idno>
<imprint><date when="2020" type="published">2020</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cell Nucleus (genetics)</term>
<term>Cell Nucleus (metabolism)</term>
<term>GTP-Binding Protein alpha Subunits (chemistry)</term>
<term>GTP-Binding Protein alpha Subunits (genetics)</term>
<term>GTP-Binding Protein alpha Subunits (metabolism)</term>
<term>Phytophthora (enzymology)</term>
<term>Phytophthora (genetics)</term>
<term>Phytophthora (growth & development)</term>
<term>Phytophthora (pathogenicity)</term>
<term>Plant Diseases (parasitology)</term>
<term>Protein Binding (MeSH)</term>
<term>Protein Domains (MeSH)</term>
<term>Protein Transport (MeSH)</term>
<term>Protein-Serine-Threonine Kinases (chemistry)</term>
<term>Protein-Serine-Threonine Kinases (genetics)</term>
<term>Protein-Serine-Threonine Kinases (metabolism)</term>
<term>Soybeans (parasitology)</term>
<term>Spores (enzymology)</term>
<term>Spores (genetics)</term>
<term>Spores (growth & development)</term>
<term>Spores (metabolism)</term>
<term>Virulence (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Domaines protéiques (MeSH)</term>
<term>Liaison aux protéines (MeSH)</term>
<term>Maladies des plantes (parasitologie)</term>
<term>Noyau de la cellule (génétique)</term>
<term>Noyau de la cellule (métabolisme)</term>
<term>Phytophthora (croissance et développement)</term>
<term>Phytophthora (enzymologie)</term>
<term>Phytophthora (génétique)</term>
<term>Phytophthora (pathogénicité)</term>
<term>Protein-Serine-Threonine Kinases (composition chimique)</term>
<term>Protein-Serine-Threonine Kinases (génétique)</term>
<term>Protein-Serine-Threonine Kinases (métabolisme)</term>
<term>Soja (parasitologie)</term>
<term>Sous-unités alpha des protéines G (composition chimique)</term>
<term>Sous-unités alpha des protéines G (génétique)</term>
<term>Sous-unités alpha des protéines G (métabolisme)</term>
<term>Spores (croissance et développement)</term>
<term>Spores (enzymologie)</term>
<term>Spores (génétique)</term>
<term>Spores (métabolisme)</term>
<term>Transport des protéines (MeSH)</term>
<term>Virulence (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>GTP-Binding Protein alpha Subunits</term>
<term>Protein-Serine-Threonine Kinases</term>
</keywords>
<keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Protein-Serine-Threonine Kinases</term>
<term>Sous-unités alpha des protéines G</term>
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<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Phytophthora</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Phytophthora</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Phytophthora</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Cell Nucleus</term>
<term>GTP-Binding Protein alpha Subunits</term>
<term>Phytophthora</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Spores</term>
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<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Phytophthora</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Noyau de la cellule</term>
<term>Phytophthora</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Sous-unités alpha des protéines G</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Cell Nucleus</term>
<term>GTP-Binding Protein alpha Subunits</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Noyau de la cellule</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Sous-unités alpha des protéines G</term>
<term>Spores</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Maladies des plantes</term>
<term>Soja</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Plant Diseases</term>
<term>Soybeans</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Protein Binding</term>
<term>Protein Domains</term>
<term>Protein Transport</term>
<term>Virulence</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Domaines protéiques</term>
<term>Liaison aux protéines</term>
<term>Transport des protéines</term>
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<front><div type="abstract" xml:lang="en">Eukaryotic heterotrimeric guanine nucleotide-binding proteins consist of α, β, and γ subunits, which act as molecular switches to regulate a number of fundamental cellular processes. In the oomycete pathogen Phytophthora sojae, the sole G protein α subunit (Gα; encoded by PsGPA1) has been found to be involved in zoospore mobility and virulence, but how it functions remains unclear. In this study, we show that the Gα subunit PsGPA1 directly interacts with PsYPK1, a serine/threonine protein kinase that consists of an N-terminal region with unknown function and a C-terminal region with a conserved catalytic kinase domain. We generated knockout and knockout-complemented strains of PsYPK1 and found that deletion of PsYPK1 resulted in a pronounced reduction in the production of sporangia and oospores, in mycelial growth on nutrient poor medium, and in virulence. PsYPK1 exhibits a cytoplasmic-nuclear localization pattern that is essential for sporangium formation and virulence of P. sojae. Interestingly, PsGPA1 overexpression was found to prevent nuclear localization of PsYPK1 by exclusively binding to the N-terminal region of PsYPK1, therefore accounting for its negative role in sporangium formation. Our data demonstrate that PsGPA1 negatively regulates sporangium formation by repressing the nuclear localization of its downstream kinase PsYPK1.</div>
</front>
</TEI>
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<DateCompleted><Year>2020</Year>
<Month>05</Month>
<Day>04</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>05</Month>
<Day>05</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1553-7374</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>16</Volume>
<Issue>1</Issue>
<PubDate><Year>2020</Year>
<Month>01</Month>
</PubDate>
</JournalIssue>
<Title>PLoS pathogens</Title>
<ISOAbbreviation>PLoS Pathog</ISOAbbreviation>
</Journal>
<ArticleTitle>G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.</ArticleTitle>
<Pagination><MedlinePgn>e1008138</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.ppat.1008138</ELocationID>
<Abstract><AbstractText>Eukaryotic heterotrimeric guanine nucleotide-binding proteins consist of α, β, and γ subunits, which act as molecular switches to regulate a number of fundamental cellular processes. In the oomycete pathogen Phytophthora sojae, the sole G protein α subunit (Gα; encoded by PsGPA1) has been found to be involved in zoospore mobility and virulence, but how it functions remains unclear. In this study, we show that the Gα subunit PsGPA1 directly interacts with PsYPK1, a serine/threonine protein kinase that consists of an N-terminal region with unknown function and a C-terminal region with a conserved catalytic kinase domain. We generated knockout and knockout-complemented strains of PsYPK1 and found that deletion of PsYPK1 resulted in a pronounced reduction in the production of sporangia and oospores, in mycelial growth on nutrient poor medium, and in virulence. PsYPK1 exhibits a cytoplasmic-nuclear localization pattern that is essential for sporangium formation and virulence of P. sojae. Interestingly, PsGPA1 overexpression was found to prevent nuclear localization of PsYPK1 by exclusively binding to the N-terminal region of PsYPK1, therefore accounting for its negative role in sporangium formation. Our data demonstrate that PsGPA1 negatively regulates sporangium formation by repressing the nuclear localization of its downstream kinase PsYPK1.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Qiu</LastName>
<ForeName>Min</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Yaning</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Xin</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Xuan</LastName>
<ForeName>Mingrun</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Baiyu</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ye</LastName>
<ForeName>Wenwu</ForeName>
<Initials>W</Initials>
<Identifier Source="ORCID">0000-0001-7347-8935</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zheng</LastName>
<ForeName>Xiaobo</ForeName>
<Initials>X</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Govers</LastName>
<ForeName>Francine</ForeName>
<Initials>F</Initials>
<Identifier Source="ORCID">0000-0001-5311-929X</Identifier>
<AffiliationInfo><Affiliation>Laboratory of Phytopathology, Wageningen University, Wageningen, The Netherlands.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wang</LastName>
<ForeName>Yuanchao</ForeName>
<Initials>Y</Initials>
<Identifier Source="ORCID">0000-0001-5803-5343</Identifier>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu, China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2020</Year>
<Month>01</Month>
<Day>21</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>PLoS Pathog</MedlineTA>
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<ISSNLinking>1553-7366</ISSNLinking>
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<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D002467" MajorTopicYN="N">Cell Nucleus</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
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<MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
<QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName>
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<MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
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<MeshHeading><DescriptorName UI="D011485" MajorTopicYN="N">Protein Binding</DescriptorName>
</MeshHeading>
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<MeshHeading><DescriptorName UI="D017346" MajorTopicYN="N">Protein-Serine-Threonine Kinases</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013025" MajorTopicYN="N">Soybeans</DescriptorName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013170" MajorTopicYN="N">Spores</DescriptorName>
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<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="Y">growth & development</QualifierName>
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<CoiStatement>The authors have declared that no competing interests exist.</CoiStatement>
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<tree><country name="République populaire de Chine"><noRegion><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name>
</noRegion>
<name sortKey="Li, Yaning" sort="Li, Yaning" uniqKey="Li Y" first="Yaning" last="Li">Yaning Li</name>
<name sortKey="Li, Yaning" sort="Li, Yaning" uniqKey="Li Y" first="Yaning" last="Li">Yaning Li</name>
<name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name>
<name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name>
<name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name>
<name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name>
<name sortKey="Xuan, Mingrun" sort="Xuan, Mingrun" uniqKey="Xuan M" first="Mingrun" last="Xuan">Mingrun Xuan</name>
<name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name>
<name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name>
<name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name>
<name sortKey="Zhang, Baiyu" sort="Zhang, Baiyu" uniqKey="Zhang B" first="Baiyu" last="Zhang">Baiyu Zhang</name>
<name sortKey="Zhang, Xin" sort="Zhang, Xin" uniqKey="Zhang X" first="Xin" last="Zhang">Xin Zhang</name>
<name sortKey="Zhang, Xin" sort="Zhang, Xin" uniqKey="Zhang X" first="Xin" last="Zhang">Xin Zhang</name>
<name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name>
<name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name>
</country>
<country name="Pays-Bas"><region name="Gueldre (province)"><name sortKey="Govers, Francine" sort="Govers, Francine" uniqKey="Govers F" first="Francine" last="Govers">Francine Govers</name>
</region>
</country>
</tree>
</affiliations>
</record>

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   |clé=     pubmed:31961913
   |texte=   G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.
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	Serveur d'exploration Phytophthora
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Serveur d'exploration Phytophthora

G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.

G protein α subunit suppresses sporangium formation through a serine/threonine protein kinase in Phytophthora sojae.

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